Clinical References

Autologous Fat Grafting: Use of Closed Syringe Microcannula System for Enhanced Autologous Structural Grafting

This study, published in Clinical, Cosmetic and Investigational Dermatology (2013), outlines methods of acquiring autologous adipose tissue as a tissue graft and a source of adult progenitor cells in cosmetic plastic surgery. It also offers a proven protocol.

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Revascularization Determines Volume Retention and Gene Expression by Fat Grafts in Mice

Autologous fat transplantation is a popular and useful technique in plastic and reconstructive surgery, but there are still issues that need to be resolved. This study, published in Experimental Biology and Medicine (2013), addresses the issue of graft volume retention.

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Use of Microcannula Closed Syringe System for Safe and Effective Lipoaspiration and Small Volume Autologous Fat Grafting

This study, published in The American Journal of Cosmetic Surgery (2013), examines methods of acquiring autologous adipose tissue as a tissue graft and source of adult progenitor cells in cosmetic surgery.

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Understanding Adipose-Derived Stromal Vascular Fraction (AD-SVF) Cell Biology and Use on the Basis of Cellular, Chemical, Structural and Paracrine Components: A Concise Review

Advancing knowledge and understanding of the elements of homeostasis and cellular maintenance/repair has begun to transform clinical practice around biocellular therapies. The author examines concepts, such as tolerogenesis and regulatory feedback, that are critical to understanding the important contribution of Adipose-Derived Stromal Vascular Fraction (AD-SVF) in tissue maintenance and repair. Dr. Alexander also discusses the current shift toward using the intact microenvironment (non-manipulated tissue) to promote cellular proliferation and differentiation, which is brought about through complex signaling and paracrine activities.

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Autologous Fat Processing Via the Revolve System: Quality and Quantity of Fat Retention Evaluated in an Animal Model

Autologous fat grafting, commonly employed during plastic surgery procedures, remains somewhat unreliable. Procedural outcomes are compromised by graft-volume loss over time and researchers point to fat processing as the likely variable. In this 2014 publication, the authors compared the standard-of-care centrifugation and decantation with a newer, streamlined system called Revolve.

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Effect of Centrifugation and Washing on Adipose Graft Viability: A New Method to Improve Graft Efficiency

It has been shown that graft success is influenced by variables in technique for aspirating, handling and injecting adipose. Hoareau, et al. set out to discover the protocol for handling adipose that would promote tissue viability.

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