Harvest® Bone Marrow Aspirate Concentrate (BMAC®) System

Harvest Bone Marrow Aspirate Concentrate (BMAC) System
Stem cell concentration and yield as compared to five other systems used to prepare bone marrow concentrate, as shown by the data below.

Device Mean Nucleated Cell Count (106 /mL)  Mean Nucleated Cell Yield (Percent) Reference
Device Mean Nucleated Cell Count (106 /mL)  Mean Nucleated Cell Yield (Percent) Reference
Harvest® SmartPrep® 2 Multicellular Processing System 98.1 ± 61.9 70.8 ± 6.0 Kevy SV and MS Jacobson, “Comparative Analysis of Bone Marrow Concentrates Prepared by the Harvest® Terumo BCT System and the Cytomedix™ Angel® System.” 2013, unpublished raw data.
Cytomedix™ Angel® Whole Blood Separation System (Arthrex) 20.5 ± 11.2 16.1 ± 1.1
Device Mean Nucleated Cell Count (106 /mL)  Mean Nucleated Cell Yield (Percent) Reference
SmartPrep 2 System 78.32 ± 33.5 67.3 ± 10.2 Kevy SV and MS Jacobson, “Comparison of Bone Marrow Concentrates Prepared by the Harvest/Terumo BMAC® System and the Thermogenesis Res-Q™ 60 System.” 2012, unpublished raw data.
Thermogenesis Res-Q™60 BMC System 50.74 ± 16.27 43. ± 17.3
Device Mean Nucleated Cell Count (106 /mL)  Mean Nucleated Cell Yield (Percent) Reference
SmartPrep 2 System 101.48 ± 64.13 66.52 ± 19.49 Hegde V, et al., “A Prospective Comparison of Three Approved Systems for Autologous Bone Marrow Concentration Demonstrated Nonequivalency in Progenitor Cell Number and Concentration.” Journal of Orthopaedic Trauma 2014; 28(10): 591–598.
Biomet BioCue™ 90.81 ± 61.05 62.34 ± 28.29
Arteriocyte Magellan® 38.17 ± 22.58 32.55 ± 13.72
Device Mean Nucleated Cell Count (106 /mL)  Mean Nucleated Cell Yield (Percent) Reference
SmartPrep 2 System 75.4 ± 38.0 69.5 ± 4.1 Kevy SV and MS Jacobson, “Comparative Analysis of Bone Marrow Concentrate and Platelet Rich Plasma Prepared by the SmartPrep 2 System and the EmCyte Elite System.” 2014, unpublished raw data.
EmCyte Elite System 63.1 ± 51.4 45.4 ± 23.3

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